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    Home»Machine Learning & Research»The Startup Alternative with Gabriela de Queiroz – O’Reilly
    Machine Learning & Research

    The Startup Alternative with Gabriela de Queiroz – O’Reilly

    Oliver ChambersBy Oliver ChambersJune 3, 2025No Comments10 Mins Read
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    The Startup Alternative with Gabriela de Queiroz – O’Reilly
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    Generative AI within the Actual World

    Generative AI within the Actual World: The Startup Alternative with Gabriela de Queiroz



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    30m 51s


    Ben Lorica and Gabriela de Queiroz, director of AI at Microsoft, discuss startups: particularly, AI startups. How do you get observed? How do you generate actual traction? What are startups doing with brokers and with protocols like MCP and A2A? And which safety points ought to startups look ahead to, particularly in the event that they’re utilizing open weights fashions?

    Try different episodes of this podcast on the O’Reilly studying platform.

    In regards to the Generative AI within the Actual World podcast: In 2023, ChatGPT put AI on everybody’s agenda. In 2025, the problem will likely be turning these agendas into actuality. In Generative AI within the Actual World, Ben Lorica interviews leaders who’re constructing with AI. Be taught from their expertise to assist put AI to work in your enterprise.

    Factors of Curiosity

    • 0:00: Introduction to Gabriela de Queiroz, director of AI at Microsoft.
    • 0:30: You’re employed with numerous startups and founders. How have the alternatives for startups in generative AI modified? Are the alternatives increasing?
    • 0:56: Completely. The entry barrier for founders and builders is far decrease. Startups are exploding—not simply the quantity but in addition the attention-grabbing issues they’re doing.
    • 1:19: You catch startups after they’re nonetheless exploring, attempting to construct their MVP. So startups must be extra persistent in looking for differentiation. If anybody can construct an MVP, how do you distinguish your self?
    • 1:46: At Microsoft, I drive a number of strategic initiatives to assist growth-stage startups. I additionally information them in fixing actual ache factors utilizing our stacks. I’ve designed packages to highlight founders. 
    • 3:08: I do numerous engagement the place I assist startups go from the prototype or MVP to affect. An MVP will not be sufficient. I must see an actual use case and I must see some traction. Once they have actual clients, we see whether or not their MVP is working.
    • 3:49: Are you beginning to see patterns for gaining traction? Are they specializing in a selected area? Or have they got a superb dataset?
    • 4:02: If they’re fixing an actual use case in a selected area or area of interest, that is the place we see them succeed. They’re fixing an actual ache, not constructing one thing generic. 
    • 4:27: We’re each in San Francisco, and fixing a selected ache or discovering a selected area means one thing totally different. Techie founders can construct one thing that’s utilized by their mates, however there’s no income.
    • 5:03: This occurs all over the place, however there’s an even bigger tradition round that right here. I inform founders, “It’s good to present me traction.” Now we have a number of corporations that began as open supply, then they constructed a paid layer on prime of the open supply mission.
    • 5:34: You’re employed with the oldsters at Azure, so presumably you already know what precise enterprises are doing with generative AI. Are you able to give us an thought of what enterprises are beginning to deploy? What’s the stage of consolation of enterprise with these applied sciences?
    • 6:06: Enterprises are a bit bit behind startups. Startups are constructing brokers. Enterprises are usually not there but. There’s numerous heavy lifting on the information infrastructure that they should have in place. And their use instances are advanced. It’s much like Huge Knowledge, the place the enterprise took longer to optimize their stack.
    • 7:19: Are you able to describe why enterprises must modernize their knowledge stack? 
    • 7:42: Actuality isn’t magic. There’s numerous complexity in knowledge and the way knowledge is dealt with. There may be numerous knowledge safety and privateness that startups aren’t conscious of however are essential to enterprises. Even the varieties of knowledge—the information isn’t effectively organized, there are totally different groups utilizing totally different knowledge sources.
    • 8:28: Is RAG now a well-established sample within the enterprise?
    • 8:44: It’s. RAG is a part of everyone’s workflow.
    • 8:51: The frequent use instances that appear to be additional alongside are buyer assist, coding—what different buckets are you able to add?
    • 9:07: Buyer assist and tickets are among the many important pains and use instances. And they’re very costly. So it’s a simple win for enterprises after they transfer to GenAI or AI brokers. 
    • 9:48: Are you saying that the instrument builders are forward of the instrument consumers?
    • 10:05: You’re proper. I discuss loads with startups constructing brokers. We talk about the place the business is heading and what the challenges are. For those who assume we’re near AGI, attempt to construct an agent and also you’ll see how far we’re from AGI. Once you need to scale, there’s one other stage of issue. Once I ask for actual examples and clients, the bulk are usually not there but.
    • 11:01: A part of it’s the terminology. Folks use the time period “agent” even for a chatbot. There’s numerous confusion. And startups are hyping the notion of multiagents. We’ll get there, however let’s begin with single brokers first. And you continue to want a human within the loop. 
    • 11:40: Sure, we discuss in regards to the human within the loop on a regular basis. Even people who find themselves bragging, while you ask them to indicate you, they’re not there but.
    • 12:00: On the agent entrance, if I requested you for a brief presentation with three slides of examples that caught your consideration, what would they be?
    • 12:30: There’s an organization doing an AI agent with emails and your calendar. Everybody makes use of e mail and calendars all day lengthy. If we need to schedule dinner with a gaggle of mates, however we’ve got individuals with dietary restrictions, it will take perpetually to discover a restaurant that checks all of the packing containers. There’s an organization attempting to make this automated.
    • 14:22: In latest months, builders have rallied round MCP and now A2A. Somebody requested me for a listing of vetted MCP servers. If the server comes from the corporate that developed the applying, superb. However there are millions of servers, and I’m cautious. We have already got software program provide chain points. Is MCP taking off, or is it a brief repair?
    • 15:48: It’s too early to say that that is it. There’s additionally the Google protocol (A2A); IBM created a protocol; that is an ongoing dialogue, and since it’s evolving so quick, one thing will in all probability come within the subsequent few months.
    • 16:31: It’s very very like the web and the requirements that emerged from there. You may make it formal, or you possibly can simply construct it, develop it, and one way or the other it turns into an empirical open customary.
    • 17:15: We’re implicitly speaking about textual content. Have you ever began to see near-production use instances involving multimodal fashions?
    • 17:37: We’ve seen some use instances with multimodality, which is extra advanced.
    • 17:48: Now you must increase your knowledge technique to all these totally different knowledge varieties.
    • 18:07: Going again to the slides: If I had three slides, I’d attempt to get everybody on the identical web page about what an AI agent is. All the massive corporations have their very own definitions. I’d set the stage with my definition: a system that may take motion in your half. Then I’d say, if you happen to assume we’re near AGI, attempt to construct an agent. And the third slide could be to construct one agent, somewhat than a multiagent. Begin small, after which you possibly can scale, not the opposite means round.
    • 19:44: Orchestration of 1 agent is one factor. Lots of people throw across the time period orchestration. For knowledge engineering, orchestration means one thing particular, and loads goes into it, even for a single agent. For multiagents, it’s much more advanced. There’s orchestration and there’s communication too. An agent could withhold, ignore, or misunderstand info. So stick to one agent. Get that achieved and transfer ahead.
    • 20:33: The large factor within the foundational mannequin area is reasoning. What has reasoning opened up for a few of these startups? What purposes depend on a reasoning-enhanced mannequin? What mannequin ought to I exploit, and may I get by with a mannequin that doesn’t purpose?
    • 21:15: I haven’t seen any startup utilizing reasoning but. Most likely due to what you might be speaking about. It’s costly, it’s slower, and startups must see wins quick. 
    • 21:46: They only ask for extra free credit.
    • 21:51: Free credit are usually not perpetually. However it’s not even the fee—it’s additionally the method and the ready. What are the trade-offs? I haven’t seen startups speaking with me about utilizing reasoning.
    • 22:22: The sound recommendation for anybody constructing something is to be mannequin agnostic. Design what you’re doing so you need to use a number of fashions or swap fashions. We now have open weights fashions which are changing into extra aggressive. Final yr we had Llama; now we even have Qwen and DeepSeek, with an unimaginable launch cadence. Are you seeing extra startups choosing open weights?
    • 23:19: Positively. However they must be very cautious after they use open fashions due to safety. I see numerous corporations utilizing DeepSeek. I ask them about safety.
    • 23:43: Within the open weights world, you possibly can have spinoff fashions. Who vets the derivatives? Proprietary fashions have much more management. And there’s provide chain dangers, although they’re not distinctive to the open weights fashions. All of us depend upon Python and Python libraries.
    • 25:17: And with individuals forking spinoff fashions. . . We’ve seen this with merchandise as effectively; individuals constructing merchandise and being worthwhile on prime of open supply initiatives. Folks constructed on a fork of a Python mission or prime of Python libraries and [became] worthwhile. 
    • 25:55: With the Chinese language open weights fashions, I’ve talked to safety individuals, and there’s nothing inherently insecure about utilizing the weights. There is perhaps architectural variations. However if you happen to’re utilizing one of many Chinese language fashions of their open API, they could have to show over knowledge. Typically, entry to the weights isn’t a standard assault vector.
    • 27:03: Or you need to use corporations like Microsoft. Now we have DeepSeek R1 accessible on Azure. However it’s gone by rigorous red-teaming and security analysis to mitigate dangers. 
    • 27:39: There are variations when it comes to alignment and red-teaming between Western and Chinese language corporations.
    • 28:26: In closing, are there any parallels between what you’re seeing now and what we noticed in knowledge science?
    • 28:40: It’s comparable, however the scale and velocity are totally different. There are extra assets and accessibility. The barrier to entry is decrease. 
    • 29:06: The hype cycle is similar. You keep in mind all of the tales about “Knowledge science is the attractive new job.” However the know-how is now far more accessible, and there are much more tales and extra pleasure.
    • 29:29: Again then, we solely had a number of choices: Hadoop, Spark. . . Not like 100 totally different fashions. And so they weren’t accessible to most people. 
    • 30:03: Again then individuals didn’t want Hadoop or MapReduce or Spark in the event that they didn’t have a lot of knowledge. And now, you don’t have to make use of the brightest or best-benchmarked LLM; you need to use a small language mannequin.
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